ISSN 1662-4009 (online)

ey0017.9-8 | New Fertility Preservation Strategies: Lights and Shadows | ESPEYB17

9.8. Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?

P Kadam , E Ntemou , J Onofre , D Van Saen , E Goossens

To read the full abstract: Stem Cell Res Ther. 2019 Oct 22;10(1):310. ellen.goossens@vub.beInfertility due to spermatogonial stem cell (SSC) loss is one of the major late adverse effects related to both chemotherapy and radiotherapy, and several researchers are now focusing on the development of new techniques to preserve germ cells.Semen sample storage is not feasible in prepuber...

ey0016.9-9 | Fertility Issues in Chronic Diseases: New Insights | ESPEYB16

9.9. Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice

P Kadam , E Ntemou , Y Baert , S Van Laere , D Van Saen , E Goossens

To read the full abstract: Stem Cell Res Ther. 2018 Nov 21; 9 (1):317Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) in animal models is about 12%, and the effectiveness of this procedure needs to be improved before clinical imple...